2013 ACC/AHA Guideline on the Treatment of Blood Cholesterol to Reduce Atherosclerotic Cardiovascular Risk in Adults

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Circulation

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Sequence Variations in <i>PCSK9,</i> Low LDL, and Protection against Coronary Heart Disease

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New England Journal of Medicine

Mutations in PCSK9 cause autosomal dominant hypercholesterolemia

Marianne Abifadel, Mathilde Varret, Jean‐Pierre Rabès, +23

Nature Genetics

Genetic DisorderGeneticsPathologyHyperlipidemiaMedicine +2

Efficacy and Safety of Alirocumab in Reducing Lipids and Cardiovascular Events

Jennifer G. Robinson, Michel Farnier, Michel Krempf, +13

New England Journal of Medicine

Efficacy and Safety of Evolocumab in Reducing Lipids and Cardiovascular Events

Marc S. Sabatine, Robert P. Giugliano, Stephen D. Wiviott, +10

New England Journal of Medicine

Heart FailureLipid PeroxidationHyperlipidemiaPharmacotherapyOxidative Stress +17

Combined analysis of oligonucleotide microarray data from transgenic and knockout mice identifies direct SREBP target genes

Jay D. Horton, Nila Shah, Janet A. Warrington, +4

Proceedings of the National Academy of Sciences

GeneticsOligonucleotide Microarray DataSrebp IsoformMolecular GeneticsGene Expression Profiling +14

Development of Antidrug Antibodies Against Adalimumab and Association With Disease Activity and Treatment Failure During Long-term Follow-up

G. M. Bartelds

JAMA

Decreased plasma cholesterol and hypersensitivity to statins in mice lacking <i>Pcsk9</i>

Shirya Rashid, David E. Curtis, Rita Garuti, +6

Proceedings of the National Academy of Sciences

Molecular Characterization of Loss-of-Function Mutations in PCSK9 and Identification of a Compound Heterozygote

Zhenze Zhao, Yetsa Tuakli-Wosornu, Thomas A. Lagace, +5

The American Journal of Human Genetics

Molecular CharacterizationGenetic DisorderMedicineGeneticsMolecular Biology +9

NARC-1/PCSK9 and Its Natural Mutants

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Journal of Biological Chemistry