Concepedia

Effect of ambient light on IgG1 monoclonal antibodies during drug product processing and development

Alavattam Sreedhara, Jian Yin, Michael Joyce, Kimberly S. F. Lau, Aaron T. Wecksler, Galahad Deperalta, Li Yi, Y. John Wang, Bruce Kabakoff, Ravuri S. K. Kishore

European Journal of Pharmaceutics and Biopharmaceutics · 2015 · 99 citations · 23 references

DOI

Concepts

References

23

Challenges in the development of high protein concentration formulations

Zahra Shahrokh, Jun 军 Liu 刘 · Journal of Pharmaceutical Sciences · 2004 · 879 citations

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Antioxidants for Prevention of Methionine Oxidation in Recombinant Monoclonal Antibody HER2

Xanthe M. Lam, Janet Yang, Jeffrey L. Cleland · Journal of Pharmaceutical Sciences · 1997 · 265 citations

, , +14

Characterization of the photodegradation of a human IgG1 monoclonal antibody formulated as a high-concentration liquid dosage form

Pei Qi, David B. Volkin, Hui Zhao et al. · Journal of Pharmaceutical Sciences · 2008 · 146 citations · Full text

, , +11

Discovery and Characterization of a Photo-Oxidative Histidine-Histidine Cross-Link in IgG1 Antibody Utilizing <sup>18</sup>O-Labeling and Mass Spectrometry

Min Liu, Zhongqi Zhang, Janet Cheetham et al. · Analytical Chemistry · 2014 · 108 citations · Full text

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A Critical Assessment of the ICH Guideline on Photostability Testing of New Drug Substances and Products (Q1B): Recommendation for Revision

Steven W. Baertschi, Karen M. Alsante, Hanne Hjorth Tønnesen · Journal of Pharmaceutical Sciences · 2010 · 107 citations

, , +11