Concepedia
Experimental Cell Research · 2015 · 59 citations · 19 references
InflammationRheumatologyRheumatoid DisorderAutoimmune DiseaseTigit OverexpressionRheumatic DiseasesT-regulatory CellImmunologyOsteoarthritisAutoimmunityInflammatory Rheumatic DiseaseCd4 T CellsMedicineCell BiologyRheumatoid Arthritis
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Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method
Kenneth J. Livak, Thomas D. Schmittgen · Methods · 2001 · 176.9K citations
Functional Genomics, Engineering, Medicine +12
The interaction of TIGIT with PVR and PVRL2 inhibits human NK cell cytotoxicity
Noa Stanietsky, Hrvoje Šimić, Jurica Arapović et al. · Proceedings of the National Academy of Sciences · 2009 · 3.5K citations · Full text
Natural Killer Cells, Human Nk Cells, Cancer Immunosurveillance +13
The surface protein TIGIT suppresses T cell activation by promoting the generation of mature immunoregulatory dendritic cells
Xin Yu, Kristin Harden, Lino C. Gonzalez et al. · Nature Immunology · 2008 · 1.4K citations
T Cell Activation, Signal Transduction, Autoimmune Disease +12
The Immunoreceptor TIGIT Regulates Antitumor and Antiviral CD8 + T Cell Effector Function
Robert J. Johnston, Laëtitia Comps‐Agrar, Jason A. Hackney et al. · Cancer Cell · 2014 · 1.1K citations · Full text
Cancer Immunosurveillance, Immunology, Tumor Immunity +6
Treg Cells Expressing the Coinhibitory Molecule TIGIT Selectively Inhibit Proinflammatory Th1 and Th17 Cell Responses
Nicole Joller, Ester Lozano, Patrick R. Burkett et al. · Immunity · 2014 · 917 citations · Full text
Inflammation, Cytokine, Autoimmune Disease +11