<i><scp>ALK</scp></i>,<i><scp>ROS</scp>1</i> and <i><scp>NTRK</scp>3</i> gene rearrangements in inflammatory myofibroblastic tumours

Abstract

These results suggest that a subset of ALK-negative IMTs have rearrangement of ROS1, ETV6 or NTRK3 as a possible oncogenic mechanism, and that the detection of these alterations may be of diagnostic value and helpful for determining promising therapeutic strategies.