Bio-inspired polymer envelopes around adenoviral vectors to reduce immunogenicity and improve in vivo kinetics

Gene therapy - promises, problems and prospects

Inder M. Verma, Nikunj V. Somia · Nature · 1997 · 1.7K citations

Medicine, Biotechnology, Molecular Biology +10

A Novel Non-Viral Vector for DNA Delivery Based on Low Molecular Weight, Branched Polyethylenimine: Effect of Molecular Weight on Transfection Efficiency and Cytotoxicity

Dagmar Fischer, Thorsten Bieber, Youxin Li et al. · Pharmaceutical Research · 1999 · 1.2K citations

Pharmacy, Biotechnology, Pharmaceutics +17

An Adenovirus Vector with Genetically Modified Fibers Demonstrates Expanded Tropism via Utilization of a Coxsackievirus and Adenovirus Receptor-Independent Cell Entry Mechanism

Igor P. Dmitriev, Victor Krasnykh, C. Ryan Miller et al. · Journal of Virology · 1998 · 769 citations · Full text

Life Sciences, Molecular Biology, Oncology +15

Adenovirus Serotype 5 Hexon Mediates Liver Gene Transfer

Simon N. Waddington, John H. McVey, David Bhella et al. · Cell · 2008 · 646 citations · Full text

Life Sciences, Molecular Biology, Molecular Genetics +13

Adenoviral Gene Therapy Leads to Rapid Induction of Multiple Chemokines and Acute Neutrophil-Dependent Hepatic Injury in Vivo

Daniel A. Muruve, Isaac E. Stillman, Towia A. Libermann · Human Gene Therapy · 1999 · 446 citations

Life Sciences, Immunology, Infectious Diseases +17