Concepedia

Phase II Study of Bryostatin 1 in Patients with Relapsed Multiple Myeloma

Mary Varterasian, Pamela Pemberton, Kim Hulburd, Dorothy H. Rodriguez, Anthony J. Murgo, Ayad Al‐Katib

Investigational New Drugs · 2001 · 42 citations · 8 references

DOI

Concepts

References

8

Isolation and structure of bryostatin 1

George R. Pettit, Cherry L. Herald, Dennis L. Doubek et al. · Journal of the American Chemical Society · 1982 · 655 citations

, , +6

Bryostatin, an activator of the calcium phospholipid-dependent protein kinase, blocks phorbol ester-induced differentiation of human promyelocytic leukemia cells HL-60.

Andrew S. Kraft, Jeffrey B. Smith, Roger L. Berkow · Proceedings of the National Academy of Sciences · 1986 · 257 citations · Full text

, , +12

Phase I study of bryostatin 1 in patients with relapsed non-Hodgkin's lymphoma and chronic lymphocytic leukemia.

Mary Varterasian, Ramzi M. Mohammad, D. Eilender et al. · Journal of Clinical Oncology · 1998 · 112 citations

, , +16

Phase II trial of bryostatin 1 in patients with relapsed low-grade non-Hodgkin's lymphoma and chronic lymphocytic leukemia.

Mary Varterasian, Ramzi M. Mohammad, Muhammad Shurafa et al. · PubMed · 2000 · 97 citations

, , +17

Bryostatin 1 down-regulates mdr1 and potentiates vincristine cytotoxicity in diffuse large cell lymphoma xenografts.

Ayad Al‐Katib, Mitchell R. Smith, W S Kamanda et al. · PubMed · 1998 · 65 citations

, , +11