Antibacterial Activity and Phytochemical Screening of Phyllanthus niruri in Ethanolic, Methanolic and Aqueous Extracts

Abstract

The medicinal plants represent an enormous reservoir of potential phytochemical compounds that could be useful as an alternative to allopathic drugs and are being used to develop Pharma drugs. Phyllanthus niruri has medicinal properties for the effective management of several aliments including Hepatitis. The present investigation was aimed to focus on the screening of phytochemical constituents. The present investigation was aimed to focus on the screening of phytochemical constituents, antibacterial activity of phyllanthus and antibacterial activity of Phyllanthus niruri in aqueous, ethanolic and methanolic extracts. PN shows Saponins, tannins, flavonoids, steroids, cardiac glycosides etc. Different concentrations of methanol, ethanol and aqueous extracts were used for antibacterial activity. Maximum zone of inhibition was observed in 30% w/v Methanolic extract than other extracts. Different extracts of P.niruri has the medicinally useful secondary metabolites and also act as antibacterial agent on various bacterial strains. The presence of these phytochemicals in PN can act as the therapeutic agents and they are responsible for free radical scavenging and antibacterial activity.