IN-VITRO ANTIOXIDANT ACTIVITY OF TECTONA GRANDIS LINN.

Abstract

Summary Free radicals are implicated in many diseases like diabetes, inflammation, cancer, which leads to gained more attraction of antioxidant therapy. The present study deals with in-vitro antioxidant activity of ethanolic extract of Tectona grandis Linn. (TG) by using DPPH assay, FRAP scavenging assay and H2O2 radical scavenging assay. The IC50 value observed in DPPH and H2O2 radical scavenging assay were 37.5 µg/ml, 32.0 µg/ml respectively, and 50 % reduction in ferricynide complex at 190 µg/ml concentration. The results were compared with ascorbic acid as a standard. Hence antioxidant property of TG may be due to presence of tannins and saponins. These results clearly indicate that TG is effective against free radical mediated diseases.