Concepedia

Feasibility and relevance of global expression profiling of gene transcripts in serum from breast cancer patients using whole genome microarrays and quantitative RT-PCR.

Lorraine O’Driscoll, Elaine Kenny, Jai Prakash Mehta, Padraig Doolan, Helena Joyce, Patrick Gammell, Arnold Hill, Brendan O’Daly, Donal J. O’Gorman, Martin Clynes

PubMed · 2008 · 30 citations · 21 references

Abstract

The potential implication of this novel finding is that using microarrays it may be possible to identify a panel of extracellular mRNAs that are diagnostic, prognostic and/or predictive of outcome for cancer patients.

References

21

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

Kenneth J. Livak, Thomas D. Schmittgen · Methods · 2001 · 176.9K citations

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Model-based analysis of oligonucleotide arrays: Expression index computation and outlier detection

Cheng Li, Wing Hung Wong · Proceedings of the National Academy of Sciences · 2000 · 3.2K citations · Full text

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Salivary Transcriptome Diagnostics for Oral Cancer Detection

Yang Li, Maie A.R. St. John, Xiaofeng Zhou et al. · Clinical Cancer Research · 2004 · 622 citations · Full text

Stability of Endogenous and Added RNA in Blood Specimens, Serum, and Plasma

Nancy B. Y. Tsui, Enders K. O. Ng, YM Dennis Lo · Clinical Chemistry · 2002 · 613 citations

Detection of tumor messenger RNA in the serum of patients with malignant melanoma.

MICHAEL S. KOPRESKI, Floyd A. Benko, Larry W. Kwak et al. · PubMed · 1999 · 364 citations

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