Concepedia

Improved assay of 3-hydroxy-3-methylglutaryl coenzyme A reductase

Stanley Goldfarb, Henry C. Pitot

Journal of Lipid Research · 1971 · 175 citations · 10 references

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Abstract

Two improvements are described for the assay of HMG CoA reductase. These are a simple synthesis of the substrate precursor HMG-3-(14)C anhydride and a double-label ((14)C and (3)H) method for determining the amount of mevalonate-3-(14)C that is formed from the substrate.

References

10

DETERMINATION OF SERUM PROTEINS BY MEANS OF THE BIURET REACTION

Allan G. Gornall, Charles J. Bardawill, Maxima M. David · Journal of Biological Chemistry · 1949 · 16.2K citations · Full text

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A SPECIFIC MICROMETHOD FOR THE DETERMINATION OF ACYL PHOSPHATES

Fritz Lipmann, L.Constanc. Tuttle · Journal of Biological Chemistry · 1945 · 1.4K citations · Full text

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Feedback Control of Mevalonate Synthesis by Dietary Cholesterol

Marvin D. Siperstein, Violet M. Fagan · Journal of Biological Chemistry · 1966 · 332 citations · Full text

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β-hydroxy-β-methylglutaryl coenzyme a reductase, cleavage and condensing enzymes in relation to cholesterol formation in rat liver

Nancy L. R. Bucher, Peter Overath, Feodor Lynen · Biochimica et Biophysica Acta · 1960 · 289 citations

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The Effect of Cholesterol Feeding and Fasting upon β-Hydroxy-β-methylglutaryl Coenzyme A Reductase

Tracy C. Linn · Journal of Biological Chemistry · 1967 · 161 citations · Full text

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