2006 · 21 citations · 11 references
Life SciencesMicrobiologyPharmacologyAntimicrobial PharmacologyAntimicrobial ResistanceMedical MicrobiologyAntibacterial PharmacologyAntibacterial PharmacotherapyAntibiotic ResistanceAntimicrobial Resistance PreventionCombination Antimicrobial TherapyResistance In Gram-negative BacteriaAntimicrobial Natural ProductsBactericidal AgentsBioactive ConstituentsExtraction Of Essential OilsMultidrug-resistant OrganismsMultidrug-resistant PathogensPseudomonas Aeruginosa ResistanceSynergy Effects
The inhibitory effects of essential oils including clove, lavender and geranium extracted from Eugenia caryophyllata, Lavandula officinalis and Pelargonium graveolens on multidrug resistant isolates of Pseudomonas aeruginosa were investigated. The main constituents of clove, lavander and geranium oil were eugenol (80-90%), 1,8-cineol (13%) and citronellol (45%) respectively. Clove had the most effective essential oil against P. aeruginosa. A combination consisting of clove, lavender and geranium oils at a ratio of 3:1:1 showed the most inhibitory effect (32-64 pg/ml) and strong synergy with gentamicin. The essential oils from clove,
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