Concepedia

2-Methoxyestradiol, an Endogenous Estrogen Metabolite, Induces Apoptosis in Endothelial Cells and Inhibits Angiogenesis: Possible Role for Stress-Activated Protein Kinase Signaling Pathway and Fas Expression

Tianli Yue, Xinkang Wang, Calvert Louden, Shalley K. Gupta, Kodandaram Pillarisetti, Juan-Li Gu, Timothy K. Hart, Paul G. Lysko, Giora Feuerstein

Molecular Pharmacology · 1997 · 187 citations · 38 references

DOI

Concepts

References

38

Opposing Effects of ERK and JNK-p38 MAP Kinases on Apoptosis

Zhengui Xia, Martin Dickens, Joël Raingeaud et al. · Science · 1995 · 5.3K citations

, , +16

JNK1: A protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain

Benoit Dérijard, Masahiko Hibi, I‐Huan Wu et al. · Cell · 1994 · 3.2K citations

, , +10

The stress-activated protein kinase subfamily of c-Jun kinases

John Kyriakis, Papia T. Banerjee, Eleni Nikolakaki et al. · Nature · 1994 · 2.6K citations

, , +13

Integrin αvβ3 antagonists promote tumor regression by inducing apoptosis of angiogenic blood vessels

Peter C. Brooks, Anthony M.P. Montgomery, Mauricio Rosenfeld et al. · Cell · 1994 · 2.3K citations

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Identification of an oncoprotein- and UV-responsive protein kinase that binds and potentiates the c-Jun activation domain.

Masahiko Hibi, Anning Lin, Tod Smeal et al. · Genes & Development · 1993 · 1.9K citations · Full text

, , +15