Protein disulfide isomerase ameliorates β-cell dysfunction in pancreatic islets overexpressing human islet amyloid polypeptide

β-Cell Deficit and Increased β-Cell Apoptosis in Humans With Type 2 Diabetes

Alexandra E. Butler, Juliette Janson, Susan Bonner‐Weir et al. · Diabetes · 2003 · 4K citations

Medicine, Endocrinology, Physiology +17

Chemical Chaperones Reduce ER Stress and Restore Glucose Homeostasis in a Mouse Model of Type 2 Diabetes

Umut Özcan, Erkan Yılmaz, Lale Özcan et al. · Science · 2006 · 2.4K citations · Full text

Life Sciences, Biochemistry, Pharmacology +17

Protein disulfide isomerase

B WILKINSON · Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics · 2004 · 554 citations

Chaperones increase association of tau protein with microtubules

Fei Dou, William J. Netzer, Kentaro Tanemura et al. · Proceedings of the National Academy of Sciences · 2003 · 461 citations · Full text

Life Sciences, Molecular Biology, Neuroscience +17

High Expression Rates of Human Islet Amyloid Polypeptide Induce Endoplasmic Reticulum Stress–Mediated β-Cell Apoptosis, a Characteristic of Humans With Type 2 but Not Type 1 Diabetes

Chang-jiang Huang, Chia‐Yu Lin, Leena Haataja et al. · Diabetes · 2007 · 410 citations · Full text

Life Sciences, Cell Biology, Endocrinology +17