α1D-Adrenergic Receptors and Mitogen-Activated Protein Kinase Mediate Increased Protein Synthesis by Arterial Smooth Muscle

A synthetic inhibitor of the mitogen-activated protein kinase cascade.

David T. Dudley, Long Pang, Stuart J. Decker et al. · Proceedings of the National Academy of Sciences · 1995 · 2.7K citations · Full text

Life Sciences, Biochemistry, Pharmacology +15

Phosphatidylinositol 3-Kinase Is an Early Intermediate in the Gβγ-mediated Mitogen-activated Protein Kinase Signaling Pathway

Brian E. Hawes, Louis M. Luttrell, Tim van Biesen et al. · Journal of Biological Chemistry · 1996 · 373 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +12

Myocardial expression of a constitutively active alpha 1B-adrenergic receptor in transgenic mice induces cardiac hypertrophy.

Carmelo A. Milano, Paul C. Dolber, Howard A. Rockman et al. · Proceedings of the National Academy of Sciences · 1994 · 371 citations · Full text

Life Sciences, Molecular Biology, Physiology +16

BMY 7378 is a selective antagonist of the D subtype of α1-adrenoceptors

Aaron S. Goetz, Holly K. King, Stuart D.C. Ward et al. · European Journal of Pharmacology · 1995 · 302 citations

Medicine, Medicinal Chemistry, Pharmacology +11

The alpha 1A-adrenergic receptor subtype mediates biochemical, molecular, and morphologic features of cultured myocardial cell hypertrophy

Kirk U. Knowlton, Martin C. Michel, M. Itani et al. · Journal of Biological Chemistry · 1993 · 300 citations · Full text

Life Sciences, Pharmacology, Physiology +13