ANTICONVULSANT AND MYORELAXATION ACTIVITY OF ANACYCLUS PYRETHRUM DC. (AKARKARA) ROOT EXTRACT

Abstract

Summary Objective: To study the anticonvulsant activity of ethanolic extract of Anacyclus pyrethrum in albino mice. Materials and methods: The anticonvulsant and myorelaxation activity of ethanolic extract of roots of Anacyclus pyrethrum (200, 400 & 600mg/kg., i.p.) was assessed using albino mice against maximum electroshock seizure (MES) test and rotarod test respectively. Result: The ethanolic extract of Anacyclus pyrethrum reduced the duration of hind limb tonic extension (HLTE) in a dose dependent manner against MES model. Conclusion: The ethanolic extract of Anacyclus pyrethrum inhibits MES-induced convulsions.