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Oxaliplatin resistance induced by ERCC1 up-regulation is abrogated by siRNA-mediated gene silencing in human colorectal cancer cells.

32

Citations

20

References

2010

Year

Raviraja N. Seetharam, Arjun B. Sood, Atrayee Basu-Mallick, Leonard H. Augenlicht, John M. Mariadason, Sanjay Goel
PubMed

Abstract

ERCC1 gene expression is inducible, contributes to oxaliplatin resistance, and is reversible by targeted suppression of ERCC1, identifying ERCC1 as a potential target for drug development.

References

YearCitations

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