Perioperative chemotherapy with fluorouracil plus leucovorin, oxaliplatin, and docetaxel versus fluorouracil or capecitabine plus cisplatin and epirubicin for locally advanced, resectable gastric or gastro-oesophageal junction adenocarcinoma (FLOT4): a randomised, phase 2/3 trial

Salah‐Eddin Al‐Batran, Nils Homann, Claudia Pauligk, +53

The Lancet

Surgical OncologyEsophageal CancerGastrointestinal OncologyMedicineVersus Fluorouracil +7

Tumour response and secondary resectability of colorectal liver metastases following neoadjuvant chemotherapy with cetuximab: the CELIM randomised phase 2 trial

Gunnar Folprecht, Thomas Gruenberger, Wolf O. Bechstein, +15

The Lancet Oncology

HepatologyGastrointestinal OncologyMedicineColorectal CancerPathology +6

Phase III Trial in Metastatic Gastroesophageal Adenocarcinoma with Fluorouracil, Leucovorin Plus Either Oxaliplatin or Cisplatin: A Study of the Arbeitsgemeinschaft Internistische Onkologie

Salah‐Eddin Al‐Batran, J. T. Hartmann, Stephan Probst, +17

Journal of Clinical Oncology

<i>ERCC1</i> and Thymidylate Synthase mRNA Levels Predict Survival for Colorectal Cancer Patients Receiving Combination Oxaliplatin and Fluorouracil Chemotherapy

Yoshinori Shirota, Jan Stoehlmacher, Jan Brabender, +7

Journal of Clinical Oncology

Thymidylate synthase gene polymorphism determines response and toxicity of 5-FU chemotherapy

Sheeja T. Pullarkat, Jan Stoehlmacher, Viviane S. Ghaderi, +7

The Pharmacogenomics Journal

Oncogenic Agent5-Fu ChemotherapyMedicinePathologyImmune-related Gene Polymorphism +4

Effect of Neoadjuvant Chemotherapy Followed by Surgical Resection on Survival in Patients With Limited Metastatic Gastric or Gastroesophageal Junction Cancer

Salah‐Eddin Al‐Batran, Nils Homann, Claudia Pauligk, +25

JAMA Oncology

Association Between Glutathione S-Transferase P1, T1, and M1 Genetic Polymorphism and Survival of Patients With Metastatic Colorectal Cancer

Jan Stoehlmacher

JNCI Journal of the National Cancer Institute

A multivariate analysis of genomic polymorphisms: prediction of clinical outcome to 5-FU/oxaliplatin combination chemotherapy in refractory colorectal cancer

Jan Stoehlmacher, D J Park, W Zhang, +4

British Journal of Cancer

Genes GlutathioneMedicineGeneticsRefractory Colorectal CancerGenetic Epidemiology +10

A novel single nucleotide polymorphism within the 5' tandem repeat polymorphism of the thymidylate synthase gene abolishes USF-1 binding and alters transcriptional activity.

Michael V Mandola, Jan Stoehlmacher, Susan Muller‐Weeks, +4

PubMed

ChromatinTranscriptional RegulationNatural SciencesGeneticsTandem Repeat Polymorphism +12

A 6 bp polymorphism in the thymidylate synthase gene causes message instability and is associated with decreased intratumoral TS mRNA levels

Michael V Mandola, Jan Stoehlmacher, Wu Zhang, +5

Pharmacogenetics