International Journal of Drug Development and Research · 2011 · 18 citations · 19 references
Nutraceutical IngredientOrthopaedic SurgeryInflammatory ArthritisPharmaceutical ChemistryOxidative StressRheumatoid DisorderNanomedicineMedicinal ChemistryOsteoarthritisInflammatory Rheumatic DiseasePhytochemicalRheumatoid ArthritisComparative EvaluationRheumatologyBiochemistryMetal ChelatingRadical (Chemistry)PharmacologyAnti-inflammatoryNatural SciencesFree Radical ScavengingMedicineNucleic AcidsDrug Discovery
Arthritis is an inflammation of joints due to infectious, metabolic or constitutional cause usually accompanied with pain, swelling, and stiffness resulting from infection, trauma, degenerative changes, metabolic disturbances, or other causes. Free radicals damage biomolecules, including lipids, proteins and nucleic acids leading to various diseases including but not limited to arthritis. The objective of the study was to investigate and compare the free radical scavenging, metal chelating, DNA repair potential and nitric oxide inhibitory property of Trois (a nano-technology based research product indicated for the treatment of pain and inflammation associated with arthritis) and with six commercial brands.
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Free radicals in biology and medicine
General Pharmacology The Vascular System · 1991 · 17.2K citations
Teresa C.P. Dinis, Vı́tor M.C. Madeira, Leonor M. Almeida · Archives of Biochemistry and Biophysics · 1994 · 2.6K citations
Biochemistry, Peroxyl Radical Scavengers, Phenolic Derivatives +7
Antiinflammatory effects of genipin, an active principle of gardenia
Hye-Jin Koo, Yun Song, Hee-Jeong Kim et al. · European Journal of Pharmacology · 2004 · 306 citations
Biology, Inflammation, Medicine +3