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Investigation on bile acid receptor regulators. Discovery of cholanoic acid derivatives with dual G-protein coupled bile acid receptor 1 (GPBAR1) antagonistic and farnesoid X receptor (FXR) modulatory activity

Molecular PharmacologyBiochemistryBiliary TractMedicineLiver PhysiologyG Protein-coupled ReceptorDual G-proteinFarnesoid X ReceptorReceptor (Biochemistry)PharmacologyModulatory ActivityDrug Discovery