Hyperhomocysteinemia in Alzheimer dementia patients and cognitive decline after 6 months follow-up period.

Abstract

tHcy might be associated with rapid cognitive decline in AD after a 6-month follow-up period and the effect might not be directly through WMHs. tHcy level correlated with greater WMHs in the trigone area although greater lesion load by MRI was in the occipital lobe.