Antimicrobial activity of secondary metabolites and lectins from plants

Abstract

This review outlines the antimicrobial activity of secondary metabolites and lectins, compounds usually associated to defense mechanisms of plants. Secondary metabolites are separated into nitrogen compounds (alkaloids, non-protein amino acids, amines, alcamides, cyanogenic glycosides and glucosinolates) and non-nitrogen compounds (monoterpenes, diterpenes, triterpenes, tetraterpenes, sesquiterpenes, saponins, flavonoids, steroids and coumarins). Lectins are carbohydrate-binding proteins and their biological properties include cell-cell interactions. This chapter reports solvent organic extracts (mixture of secondary metabolites), isolated secondary metabolites and lectins from plants with antimicrobial activity against Gram-negative and Gram-positive bacteria as well as antifungal activity towards human and plant pathogens. Mechanisms proposed for antimicrobial activity of secondary metabolites and lectins against bacteria and fungi are also discussed. The effects of plant secondary metabolites and lectins on deleterious human and plant microorganisms indicates their perspectives of antimicrobial uses.