Evaluation of the hippocampus and the anterior cingulate gyrus by proton MR spectroscopy in patients with post-traumatic stress disorder.

Abstract

Changes in the metabolite ratios provide support for either neuronal dysfunction or neuronal loss both in the hippocampus and the anterior cingulate gyrus and may be associated with reduced neuronal integrity. Further studies with MRS in larger patient populations are needed to clarify the relationship between brain structures and neurobiology of PTSD.