Neuroprotective Effects of LY379268, a Selective mGlu2/3 Receptor Agonist: Investigations into Possible Mechanism of Action In Vivo

Delayed neuronal death in the gerbil hippocampus following ischemia

Takaaki Kirino · Brain Research · 1982 · 2.9K citations

Life Sciences, Neurobiology, Neuroscience +14

Induced Tolerance to Ischemia in Gerbil Hippocampal Neurons

Takaaki Kirino, Yoshihiko Tsujita, Akira Tamura · Journal of Cerebral Blood Flow & Metabolism · 1991 · 585 citations

Life Sciences, Neurobiology, Neuroscience +13

The metabotropic glutamate receptors, MGLUR2 and MGLUR3, show unique postsynaptic, presynaptic and glial localizations

Ronald S. Petralia, Y.-X. Wang, A.S. Niedzielski et al. · Neuroscience · 1996 · 583 citations

Life Sciences, Neurobiology, Neuroscience +14

LY341495 is a nanomolar potent and selective antagonist of group II metabotropic glutamate receptors

Anne Kingston, Paul L. Ornstein, Rebecca A. Wright et al. · Neuropharmacology · 1998 · 365 citations

Life Sciences, Neuroscience, Pharmacology +16

Synthesis, Pharmacological Characterization, and Molecular Modeling of Heterobicyclic Amino Acids Related to (+)-2-Aminobicyclo[3.1.0]hexane- 2,6-dicarboxylic Acid (LY354740):  Identification of Two New Potent, Selective, and Systemically Active Agonists for Group II Metabotropic Glutamate Receptors

James A. Monn, Matthew J. Valli, Steven M. Massey et al. · Journal of Medicinal Chemistry · 1999 · 288 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17