Pyrazolo[4,3-d]pyrimidines as new generation of cyclin-dependent kinase inhibitors

Exploiting Chemical Libraries, Structure, and Genomics in the Search for Kinase Inhibitors

Nathanael S. Gray, Lisa Wodicka, A.M.W.H. Thunnissen et al. · Science · 1998 · 808 citations · Full text

Pharmacy, Medicinal Chemistry, Molecular Biology +15

Inhibition of Cyclin‐Dependent Kinases by Purine Analogues

Jaroslav Veselý, Libor Havlı́ček, Miroslav Strnad et al. · European Journal of Biochemistry · 1994 · 626 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +16

Cytokinin-Derived Cyclin-Dependent Kinase Inhibitors:  Synthesis and cdc2 Inhibitory Activity of Olomoucine and Related Compounds

Libor Havlı́ček, Jan Hanuš, Jaroslav Veselý et al. · Journal of Medicinal Chemistry · 1997 · 242 citations · Full text

Life Sciences, Medicinal Chemistry, Molecular Biology +17

Synthesis and biological activity of olomoucine II

Vladimı́r Kryštof, René Lenobel, Libor Havlı́ček et al. · Bioorganic & Medicinal Chemistry Letters · 2002 · 69 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +8

Docking-Based Development of Purine-like Inhibitors of Cyclin-Dependent Kinase-2

Michal Otyepka, Vladimı́r Kryštof, Libor Havlı́ček et al. · Journal of Medicinal Chemistry · 2000 · 65 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17