Concepedia

A versatile approach to flavones via a one-pot Pd(<scp>ii</scp>)-catalyzed dehydrogenation/oxidative boron-Heck coupling sequence of chromanones

Jun Lee, Jihyun Yu, Seung Hwan Son, Jinyuk Heo, Tae‐Lim Kim, Ji‐Young An, Kyung‐Soo Inn, Nam‐Jung Kim

Organic & Biomolecular Chemistry · 2015 · 37 citations · 56 references

DOI

Concepts

Abstract

A variety of flavones were expediently synthesized from readily accessible chromanones via a one-pot sequence involving Pd(II)-catalyzed dehydrogenation and oxidative boron-Heck coupling with arylboronic acid pinacol esters. In particular, the use of arylboronic acid pinacol esters was found to significantly improve the yield of the reaction.

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