Concepedia

Synthesis and structure–activity relationships of novel IKK-β inhibitors. Part 2: Improvement of in vitro activity

Toshiki Murata, Mitsuyuki Shimada, Hiroshi KADONO, Sachiko Sakakibara, Takashi Yoshino, Tsutomu Masuda, Makoto Shimazaki, Takuya Shintani, Kinji Fuchikami, Kevin B. Bacon,

Bioorganic & Medicinal Chemistry Letters · 2004 · 71 citations · 7 references

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References

7

IKK-1 and IKK-2: Cytokine-Activated IκB Kinases Essential for NF-κB Activation

Frank Mercurio, Hengyi Zhu, Brion W. Murray et al. · Science · 1997 · 2K citations

, , +15

The IκB Kinase Complex (IKK) Contains Two Kinase Subunits, IKKα and IKKβ, Necessary for IκB Phosphorylation and NF-κB Activation

Ebrahim Zandi, David M. Rothwarf, Mireille Delhase et al. · Cell · 1997 · 1.8K citations · Full text

, , +9

IκB Kinase-β: NF-κB Activation and Complex Formation with IκB Kinase-α and NIK

John Woronicz, Xiong Gao, Zhaodan Cao et al. · Science · 1997 · 1.2K citations

, , +16

Discovery of novel and selective IKK-β serine-threonine protein kinase inhibitors. Part 1

Toshiki Murata, Mitsuyuki Shimada, Sachiko Sakakibara et al. · Bioorganic & Medicinal Chemistry Letters · 2003 · 172 citations · Full text

, , +6

IκB Kinases α and β Show a Random Sequential Kinetic Mechanism and Are Inhibited by Staurosporine and Quercetin

Gregory W. Peet, Jun Li · Journal of Biological Chemistry · 1999 · 102 citations · Full text

, , +13