Concepedia

Tetrahydronaphthalene-derived amino alcohols and amino ketones as potent and selective inhibitors of the delayed rectifier potassium current IKs

Saleem Ahmad, Lidia M. Doweyko, Aaila Ashfaq, Francis N. Ferrara, Sharon N. Bisaha, Joan B. Schmidt, John D. DiMarco, Mary Lee Conder, Tonya Jenkins-West, Diane E. Normandin,

Bioorganic & Medicinal Chemistry Letters · 2003 · 14 citations · 15 references

DOI

Concepts

References

15

A mechanistic link between an inherited and an acquird cardiac arrthytmia: HERG encodes the IKr potassium channel

Michael C. Sanguinetti, Changan Jiang, Mark Curran et al. · Cell · 1995 · 2.4K citations · Full text

, , +16

A molecular basis for cardiac arrhythmia: HERG mutations cause long QT syndrome

Mark Curran, Igor Splawski, Katherine W. Timothy et al. · Cell · 1995 · 2.3K citations · Full text

, , +13

A useful 12-I-5 triacetoxyperiodinane (the Dess-Martin periodinane) for the selective oxidation of primary or secondary alcohols and a variety of related 12-I-5 species

D. B. DESS, J. C. Martin · Journal of the American Chemical Society · 1991 · 2.1K citations

, , +8

Coassembly of KVLQT1 and minK (IsK) proteins to form cardiac IKS potassium channel

Michael C. Sanguinetti, Mark Curran, Anruo Zou et al. · Nature · 1996 · 1.8K citations

, , +12

KvLQT1 and IsK (minK) proteins associate to form the IKS cardiac potassium current

Jacques Barhanin, Florian Lesage, Eric Guillemare et al. · Nature · 1996 · 1.6K citations

, , +12