Concepedia

Sulfamoyl-4-oxoquinoline-3-carboxamides: Novel potentiators of defective ΔF508-cystic fibrosis transmembrane conductance regulator chloride channel gating

Yat Fan Suen, Lori I. Robins, Baoxue Yang, A. S. Verkman, Michael H. Nantz, Mark J. Kurth

Bioorganic & Medicinal Chemistry Letters · 2005 · 33 citations · 12 references

DOI

Concepts

References

12

Altered chloride ion channel kinetics associated with the ΔF508 cystic fibrosis mutation

Wilfried Dalemans, Pascal Barbry, Guy Champigny et al. · Nature · 1991 · 700 citations

, , +13

Small-molecule correctors of defective  F508-CFTR cellular processing identified by high-throughput screening

Nicoletta Pedemonte · Journal of Clinical Investigation · 2005 · 534 citations · Full text

, , +17

The Synthesis of Certain Substituted Quinolines and 5,6-Benzoquinolines

R. Gordon Gould, Walter A. Jacobs · Journal of the American Chemical Society · 1939 · 301 citations

, , +8

Nanomolar Affinity Small Molecule Correctors of Defective ΔF508-CFTR Chloride Channel Gating

Hong Yang, Anang A. Shelat, R. Kiplin Guy et al. · Journal of Biological Chemistry · 2003 · 203 citations · Full text

, , +13

Phenylglycine and Sulfonamide Correctors of Defective ΔF508 and G551D Cystic Fibrosis Transmembrane Conductance Regulator Chloride-Channel Gating

Nicoletta Pedemonte, N.D. Sonawane, Alessandro Taddei et al. · Molecular Pharmacology · 2005 · 141 citations

, , +17