The IL-15-Based ALT-803 Complex Enhances FcγRIIIa-Triggered NK Cell Responses and <i>In Vivo</i> Clearance of B Cell Lymphomas - Concepedia

Concepedia

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The IL-15-Based ALT-803 Complex Enhances FcγRIIIa-Triggered NK Cell Responses and <i>In Vivo</i> Clearance of B Cell Lymphomas

DOI Full Paper Access

143

Citations

41

References

2015

Year

Maximillian Rosario, Bai Liu, Lin Kong, Lynne Collins, Stephanie Schneider, Xiaoyue Chen, Kaiping Han, Emily K. Jeng, Peter R. Rhode, Jeffrey Leong,

Clinical Cancer Research

Abstract

ALT-803 represents a novel immunostimulatory drug that enhances NK-cell antilymphoma responses in vitro and in vivo, thereby supporting the clinical investigation of ALT-803 plus anti-CD20 mAbs in patients with indolent B-cell lymphoma.

References

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