Life SciencesBiochemistryCell BiologyCell SignalingElectrophysiologySignal TransductionIon Channel ModulationIon Channel PharmacologyIon Channel PhysiologyIon Channel RegulationIon Channel SignalingIon ChannelsG Protein Regulation Of Ion ChannelsHeterotrimeric G Protein SignalingIon Channel ActivationIon Channel FunctionIon Channel TargetsMembrane Potential CouplingMembrane Potential Disruption
Signaling between cells may be accomplished or accompanied by changes in membrane potential. The latter is regulated by ion channels, which are targets for regulatory processes initiated during signaling. Cell signaling frequently involves heterotrimeric G proteins. Evidence that ion channels are G protein effectors and functional implications of such regulation are reviewed.