Concepedia

A validated chemiluminescence immunoassay for methotrexate (MTX) and its application in a pharmacokinetic study

Zhaorui Song, Yufen Wang, Yaqing Dong, Kun Xu, Long Hao, Chuan Deng, Yongmei Yin, Sergei A. Eremin, Meng Meng, Rimo Xi

Analytical Methods · 2015 · 15 citations · 22 references

DOI

Concepts

Abstract

Polyclonal antibodies for anticancer drug methotrexate (MTX) were originally produced, and a chemiluminescence immunoassay was developed for plasma MTX determination.

References

22

Paper-based chemiluminescence ELISA: Lab-on-paper based on chitosan modified paper device and wax-screen-printing

Shoumei Wang, Lei Ge, Xianrang Song et al. · Biosensors and Bioelectronics · 2011 · 438 citations

, , +11

Methotrexate-induced renal impairment: clinical studies and rescue from systemic toxicity with high-dose leucovorin and thymidine.

H T Abelson, Martin Fosburg, G. Peter Beardsley et al. · Journal of Clinical Oncology · 1983 · 150 citations

, , +17

Miniature multi-channel SPR instrument for methotrexate monitoring in clinical samples

Sandy Shuo Zhao, Natalia Bukar, Jacynthe L. Toulouse et al. · Biosensors and Bioelectronics · 2014 · 140 citations

, , +7

Determination of methotrexate and its major metabolite, 7-hydroxymethotrexate, using capillary zone electrophoresis and laser-induced fluorescence detection

Mark Roach, Philippe Gozel, Richard N. Zare · Journal of Chromatography B Biomedical Sciences and Applications · 1988 · 120 citations

, , +16

Preparation of Anti-Tetracycline Antibodies and Development of an Indirect Heterologous Competitive Enzyme-Linked Immunosorbent Assay to Detect Residues of Tetracycline in Milk

Yulan Zhang, Shengxin Lu, Wei Liu et al. · Journal of Agricultural and Food Chemistry · 2006 · 118 citations

, , +16