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SAR of benzoylpyridines and benzophenones as p38α MAP kinase inhibitors with oral activity

Láśzló Révész, Ernst Blum, Franco E. Di Padova, Thomas Buhl, Roland Feifel, Hermann Gram, Peter Hiestand, Ute Manning, Gerard Rucklin

Bioorganic & Medicinal Chemistry Letters · 2004 · 33 citations · 7 references

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7

A convenient synthesis of acetylenes: catalytic substitutions of acetylenic hydrogen with bromoalkenes, iodoarenes and bromopyridines

Kenkichi Sonogashira, Yasuo Tohda, Nobue Hagihara · Tetrahedron Letters · 1975 · 5.1K citations

, , +11

The Palladium‐Catalyzed Cross‐Coupling Reactions of Organotin Reagents with Organic Electrophiles [New Synthetic Methods (58)]

J. K. Stille · Angewandte Chemie International Edition in English · 1986 · 3.4K citations

, , +9

13. Researches on acetylenic compounds. Part I. The preparation of acetylenic ketones by oxidation of acetylenic carbinols and glycols

K. Bowden, I. M. Heilbron, E. R. H. Jones et al. · Journal of the Chemical Society (Resumed) · 1946 · 906 citations

, , +3

Pyrazole Urea-Based Inhibitors of p38 MAP Kinase:  From Lead Compound to Clinical Candidate

John R. Regan, Steffen Breitfelder, Pier F. Cirillo et al. · Journal of Medicinal Chemistry · 2002 · 350 citations · Full text

, , +17

Oxidations with Manganese Dioxide

E. P. Papadopoulos, A. Jarrar, C. H. ISSIDORIDES · The Journal of Organic Chemistry · 1966 · 140 citations

, , +9