Serum Apolipoprotein A-1 Quantification by LC–MS with A Silac Internal Standard Reveals Reduced Levels in Smokers

Abstract

The concentration of ApoA-1 in nonsmokers was 169.4 mg/dl with an 18.4% reduction to 138.2 mg/dl in smokers. The validated assay will have clinical utility for assessing effects of smoking cessation and therapeutic or dietary interventions in high-risk populations.