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Bicyclic amidine inhibitors of nitric oxide synthase: discovery of perhydro-iminopyrindine and perhydro-iminoquinoline as potent, orally active inhibitors of inducible nitric oxide synthase

BiochemistryReactive Nitrogen SpecieMedicineActive InhibitorsNitrosative StressNitric Oxide SynthaseBicyclic Amidine InhibitorsPharmacotherapyDrug DevelopmentPharmacologyInhibitory ActivityDrug Discovery