Concepedia

Publication | Open Access

Tumor Tissue-Derived Formaldehyde and Acidic Microenvironment Synergistically Induce Bone Cancer Pain

DOIFull Paper Access

123

Citations

65

References

2010

Year

Zhiqian Tong, Wenhong Luo, Yan-Qing Wang, Fei Yang, Ying Han, Hui Li, Hongjun Luo, Bo Duan, Tian‐Le Xu, Qi‐Liang Mao‐Ying,
PLoS ONE

Abstract

Our data suggest that cancer tissues directly secrete endogenous formaldehyde, and this formaldehyde at low concentration induces metastatic bone cancer pain through TRPV1 activation especially under tumor acidic environment.

References

YearCitations

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