pH- and electro-response characteristics of bacterial cellulose nanofiber/sodium alginate hybrid hydrogels for dual controlled drug delivery

Abstract

An ionic crosslinking nanocellulose/sodium alginate (BC/SA) hybrid hydrogel was prepared as a dual-stimuli responsive release system. The drug release rate of BC/SA hybrid hydrogels <italic>in vitro</italic> not only depend on pH value but also depend on the presence of electric stimulus.