Concepedia

A butenolide intermediate in methylenomycin furan biosynthesis is implied by incorporation of stereospecifically 13C-labelled glycerols

Christophe Corre, Stuart W. Haynes, Nicolas Malet, Lijiang Song, Gregory L. Challis

Chemical Communications · 2010 · 14 citations · 6 references

DOI

Concepts

Abstract

The label from [3-(13)C]-L-glycerol is incorporated into the hydroxymethyl group of methylenomycin furans suggesting a butenolide intermediate in their biosynthesis.

References

6

Biosynthesis of γ-butyrolactone autoregulators that switch on secondary metabolism and morphological development in <i>Streptomyces</i>

Junya Kato, Nobutaka Funa, Hidenori Watanabe et al. · Proceedings of the National Academy of Sciences · 2007 · 184 citations · Full text

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2-Alkyl-4-hydroxymethylfuran-3-carboxylic acids, antibiotic production inducers discovered by <i>Streptomyces coelicolor</i> genome mining

Christophe Corre, Lijiang Song, Sean O’Rourke et al. · Proceedings of the National Academy of Sciences · 2008 · 162 citations · Full text

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A cryptic type I polyketide synthase (cpk) gene cluster in Streptomyces coelicolor A3(2)

Krzysztof Pawlik, Magdalena Kotowska, Keith Chater et al. · Archives of Microbiology · 2006 · 79 citations

, , +12

Biomimetic Synthesis of a New Class of Bacterial Signaling Molecules

Jesse B. Davis, J. Daniel Bailey, Jason K. Sello · Organic Letters · 2009 · 30 citations

, , +17

Acyl α-L-Rhamnopyranosides, a Novel Family of Secondary Metabolites fromStreptomyces sp.: Isolation and Biosynthesis

Stephanie Grond, Hans-Jörg Langer, Petra Henne et al. · European Journal of Organic Chemistry · 2000 · 27 citations

, , +12