Panipenem, A Carbapenem Antibiotic, Enhances the Glucuronidation of Intravenously Administered Valproic Acid in Rats

[4] Isolation and use of liver cells

Peter Moldéus, Johan Högberg, Sten Orrenius · Methods in enzymology on CD-ROM/Methods in enzymology · 1978 · 1.2K citations

Life Sciences, Biotechnology, Cell Biology +11

Disposition of valproic acid in the rat: dose-dependent metabolism, distribution, enterohepatic recirculation and choleretic effect.

R. G. Dickinson, Robert C. Harland, Ajmal M. Ilias et al. · Journal of Pharmacology and Experimental Therapeutics · 1979 · 126 citations

Pharmacy, Pharmacokinetics, Pharmacology +17

Effects of polytherapy with phenytoin, carbamazepine, and stiripentol on formation of 4-ene-valproate, a hepatotoxic metabolite of valproic acid

René H. Levy, Albert W. Rettenmeier, Gail D. Anderson et al. · Clinical Pharmacology & Therapeutics · 1990 · 121 citations

Pharmacy, Pharmacokinetics, Pharmacology +15

Different biliary excretion systems for glucuronide and sulfate of a model compound; study using Eisai hyperbilirubinemic rats.

Osamu Takenaka, Takeo Horie, Hiroshi Suzuki et al. · Journal of Pharmacology and Experimental Therapeutics · 1995 · 62 citations

Pharmacy, Pharmacokinetics, Pharmacology +17

Transport systems of isolated hepatocytes

Michael Schwenk · Archives of Toxicology · 1980 · 57 citations

Engineering, Biochemistry, Physiology +12