Structural Proteins of Mammalian Oncogenic RNA Viruses: Murine Leukemia Virus Neutralization by Antisera Prepared Against Purified Envelope Glycoprotein

Richard A. Steeves, Mette Strand, J. T. August

Journal of Virology · 1974 · 77 citations · 5 references

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Abstract

Goat and rabbit antisera prepared against a purified Rauscher murine leukemia virus glycoprotein (gp69/71) rapidly neutralized spleen focus-forming virus in Rauscher and Friend virus preparations. Absorption studies revealed that most of the neutralizing activity of goat anti-Rauscher virus gp69/71 serum was directed against type- and group-specific determinants.

References

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