High-grade intramedullary astrocytomas: 30 years' experience at the Neurosurgery Department of the University of Rome “Sapienza”

Abstract

Surgical treatment did not ameliorate the postoperative neurological status; instead, in the majority of cases, it prompted a worsening of the deficit. Radiotherapy and chemotherapy have a little influence on the length of survival. In this series, multimodality treatment of intramedullary high-grade astrocytomas has been shown to increase length of survival without improving the neurological status.