Nucleic Acids Research · 2012 · 564 citations · 29 references
Life SciencesMicrobiologySystems BiologyGenomicsMicrobial GeneticsMicrobial Systems BiologyGenomic DatabasesTaxonomic DatabasesCurated Bacterial DatabasesCurated Genome DatabasesExpert Manual CurationManual Annotation CurationManual CurationStrain CollectionsSystems-level Genotype-phenotype IntegrationSystems-level Modeling
EcoCyc (http://EcoCyc.org) is a model organism database built on the genome sequence of Escherichia coli K-12 MG1655. Expert manual curation of the functions of individual E. coli gene products in EcoCyc has been based on information found in the experimental literature for E. coli K-12-derived strains. Updates to EcoCyc content continue to improve the comprehensive picture of E. coli biology. The utility of EcoCyc is enhanced by new tools available on the EcoCyc web site, and the development of EcoCyc as a teaching tool is increasing the impact of the knowledge collected in EcoCyc.
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The Complete Genome Sequence of <i>Escherichia coli</i> K-12
Frederick R. Blattner, Guy Plunkett, Craig A. Bloch et al. · Science · 1997 · 7.5K citations
Adam M. Feist, Christopher S. Henry, Jennifer L. Reed et al. · Molecular Systems Biology · 2007 · 1.4K citations · Full text