Publication | Closed Access
Protein Expression, Aggregation, and Triggered Release from Polymersomes as Artificial Cell‐like Structures
181
Citations
28
References
2012
Year
EngineeringResponsive PolymersMolecular BiologyCytoskeletonCellular PhysiologyPolymersExpression MachineryProtein ExpressionTriggered ReleaseArtificial Cell‐like StructuresBiophysicsSynthetic MacromoleculeArtificial CellsRed DotsMacromolecular MachineCell EngineeringCell BiologyBiomolecular EngineeringPolymer ScienceMacromolecular SystemCell MotilityProtein EngineeringMedicinePolymer Self-assemblyExtracellular Matrix
Bringing droplets to life: A cytoskeletal protein (red dots, see scheme) is expressed in artificial cells composed of biocompatible polymersomes, which encapsulate expression machinery and amino acid building blocks. Release of the expressed proteins can be triggered by a negative osmotic shock.
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