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Glycan deletions in the HIV-1 gp120 V1/V2 domain compromise viral infectivity, sensitize the mutant virus strains to carbohydrate-binding agents and represent a specific target for therapeutic intervention

GlycoproteomicsGlycosylationBiochemistryNatural SciencesMutant Virus StrainsHuman RetrovirusGlycobiologyAntiviral ResponseMolecular BiologyVirologyAntiviral Drug DevelopmentGlycan DeletionsHivMedicineCarbohydrate-protein InteractionDrug DiscoveryTherapeutic Intervention