Concepedia

Formation of pyrazinoisoquinoline ring system by the tandem amidoalkylation and N-acyliminium ion cyclization: An efficient synthesis of Praziquantel

Joong Hyup Kim, Yong Sup Lee, Hokoon Park, Choong Sup Kim

Tetrahedron · 1998 · 49 citations · 12 references

DOI

Concepts

References

12

Comprehensive organic chemistry

D. H. R. BARTON, W. David Ollis · Tetrahedron Letters · 1978 · 2.8K citations

Intramolecular reactions of N-acyliminium intermediates

W. N. SPECKAMP, Henk Hiemstra · Tetrahedron · 1985 · 549 citations

, , +5

Synthesis and properties of praziquantel, a novel broad spectrum anthelmintic with excellent activity against Schistosomes and Cestodes

J. Seubert, R. Pohlke, F. Loebich · Cellular and Molecular Life Sciences · 1977 · 127 citations

, , +13

Praziquantel: The enigmatic antiparasitic

Tim A. Day, James L. Bennett, Ralph A. Pax · Parasitology Today · 1992 · 107 citations

, , +10

Asymmetric Synthesis of Both Enantiomers of Pyrrolidinoisoquinoline Derivatives from L-Malic Acid and L-Tartaric Acid

Yong Sup Lee, Dong Wook Kang, Sook Ja Lee et al. · The Journal of Organic Chemistry · 1995 · 70 citations

, , +8