IEEE Transactions on Nuclear Science · 2009 · 163 citations · 34 references
EngineeringRadiologyDiagnostic ImagingDiagnostic RadiologyRadiation DetectionComputed TomographyGamma-ray DetectionGamma-ray DetectorsLikelihood EstimationMaximum Likelihood EstimationRadiation Imaging DetectorsFisher InformationGamma Detector SystemsGamma-ray ImagingGamma-ray TomographyMaximum Likelihood EstimatorSignalsTomographic ImagingTomographic Reconstruction
In any gamma-ray detector, each event produces electrical signals on one or more circuit elements. From these signals, we may wish to determine the presence of an interaction; whether multiple interactions occurred; the spatial coordinates in two or three dimensions of at least the primary interaction; or the total energy deposited in that interaction. We may also want to compute listmode probabilities for tomographic reconstruction. Maximum-likelihood methods provide a rigorous and in some senses optimal approach to extracting this information, and the associated Fisher information matrix provides a way of quantifying and optimizing the information conveyed by the detector. This paper will review the principles of likelihood methods as applied to gamma-ray detectors and illustrate their power with recent results from the Center for Gamma-ray Imaging.
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Eric R. Ziegel, E. L. Lehmann, George Casella · Technometrics · 1999 · 4.3K citations
Harrison H. Barrett, Kyle J. Myers, S Rathee · Medical Physics · 2004 · 1.1K citations
Arts, Radiology, Biomedical Imaging +11