The <i>PALB2</i> Gene Is a Strong Candidate for Clinical Testing in <i>BRCA1</i> - and <i>BRCA2</i> -Negative Hereditary Breast Cancer

Abstract

Our results show that mutation analysis of the PALB2 gene, including the analysis of LGRs, is primarily indicated in patients with HBC in case of their BRCA1 and BRCA2 negativity.