A Pyridone Analogue of Traditional Cannabinoids. A New Class of Selective Ligands for the CB2 Receptor

Relationship between the inhibition constant (KI) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

Yung-Chi Cheng, William H. Prusoff · Biochemical Pharmacology · 1973 · 12.9K citations

Life Sciences, Biochemistry, Chemical Kinetics +14

Evaluation of binding in a transfected cell line expressing a peripheral cannabinoid receptor (CB2): identification of cannabinoid receptor subtype selective ligands.

Vincent M. Showalter, David M. Compton, BR Martin et al. · Journal of Pharmacology and Experimental Therapeutics · 1996 · 572 citations

Medicine, Neuroscience, Pharmacology +14

Pharmacology of Cannabinoid Receptor Ligands

Roger G. Pertwee · Current Medicinal Chemistry · 1999 · 496 citations

Medicine, Neuroscience, Pharmacology +9

Cannabinoid structure-activity relationships: correlation of receptor binding and in vivo activities.

David M. Compton, Kenner C. Rice, Barbara Costa et al. · Journal of Pharmacology and Experimental Therapeutics · 1993 · 464 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17

Behavioral, biochemical, and molecular modeling evaluations of cannabinoid analogs

Billy R. Martin, Brian F. Thomas, William R. Prescott et al. · Pharmacology Biochemistry and Behavior · 1991 · 408 citations

Pharmacy, Medicinal Chemistry, Pharmacology +11