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A Phase II Study of Sequential Methotrexate and 5-fluorouracil Chemotherapy in Previously Treated Gastric Cancer: A Report from the Gastrointestinal Oncology Group of the Japan Clinical Oncology Group, JCOG 9207 Trial

Tsuyoshi Hamaguchi, Kuniaki Shirao, Noboru Yamamichi, Ichinosuke Hyodo, Wasaburo Koizumi, S. Seki, Tetsuya Imamura, Hideyuki Honma, Atsushi Ohtsu, Narikazu Boku,

Japanese Journal of Clinical Oncology · 2008 · 21 citations · 17 references

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Abstract

Sequential MTX/5-FU therapy provides good survival outcomes with tolerable toxicity despite a limited response in patients with previously treated advanced gastric cancer. This regimen is now being evaluated in a randomized study in patients with pretreated advanced gastric cancer, by the Japan Clinical Oncology Group.

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