Concepedia

Second-line Chemotherapy

Second-Line Chemotherapy is a chemotherapeutic regimen classified as a systemic cancer treatment modality, differentiated from first-line therapy by its application upon disease progression, relapse, or inadequate response to initial treatment, particularly within the context of palliative intent or refractory childhood cancers.

1.8K

Publications

96.3K

Citations

12.3K

Authors

2.9K

Institutions

Publications per year

2017–2026

464

Parents

Publications

1.8K

Erlotinib in Previously Treated Non–Small-Cell Lung Cancer

Frances A. Shepherd, José Rodrigues Pereira, Tudor–Eliade Ciuleanu et al. · New England Journal of Medicine · 2005 · 5.5K citations · Full text

, , +15

Ramucirumab plus docetaxel versus placebo plus docetaxel for second-line treatment of stage IV non-small-cell lung cancer after disease progression on platinum-based therapy (REVEL): a multicentre, double-blind, randomised phase 3 trial

Edward B. Garon, Tudor–Eliade Ciuleanu, Óscar Arrieta et al. · The Lancet · 2014 · 1.3K citations · Full text

, , +16

Randomized Phase III Study of Panitumumab With Fluorouracil, Leucovorin, and Irinotecan (FOLFIRI) Compared With FOLFIRI Alone As Second-Line Treatment in Patients With Metastatic Colorectal Cancer

Marc Peeters, Timothy Price, Andrés Cervantes et al. · Journal of Clinical Oncology · 2010 · 1K citations

, , +15

Ramucirumab versus placebo in combination with second-line FOLFIRI in patients with metastatic colorectal carcinoma that progressed during or after first-line therapy with bevacizumab, oxaliplatin, and a fluoropyrimidine (RAISE): a randomised, double-blind, multicentre, phase 3 study

Josep Tabernero, Takayuki Yoshino, Allen Lee Cohn et al. · The Lancet Oncology · 2015 · 955 citations

, , +12

Randomized trial comparing monthly low-dose leucovorin and fluorouracil bolus with bimonthly high-dose leucovorin and fluorouracil bolus plus continuous infusion for advanced colorectal cancer: a French intergroup study.

Aimery de Gramont, J.-F. Bosset, C Milan et al. · Journal of Clinical Oncology · 1997 · 907 citations

, , +16

1–5 of 1.8K

Authors

12.3K

  1. TA
    Thierry André

    Sorbonne Université, France

    18 publications · 2.4K citations

    16

    h-index

  2. NB
    Narikazu Boku

    National Cancer Center Hospital East, Japan

    19 publications · 1.7K citations

    16

    h-index

  3. JV
    Joachim von Pawel

    Asklepios Fachkliniken München-Gauting, Germany

    18 publications · 1.6K citations

    16

    h-index

  4. MD
    Michel Ducreux

    Institut Gustave Roussy, France

    18 publications · 2K citations

    16

    h-index

  5. EV
    Eric Van Cutsem

    KU Leuven, Belgium

    18 publications · 2.8K citations

    15

    h-index

1–5 of 12.3K

Institutions

2.9K

  1. Institut Gustave Roussy

    Villejuif, France

    30 h-index

    147 publications

    17.2K citations

  2. National Cancer Center Hospital East

    Kashiwa, Japan

    27 h-index

    169 publications

    8.1K citations

  3. Sorbonne Université

    Paris, France

    26 h-index

    112 publications

    11.5K citations

  4. The University of Texas MD Anderson Cancer Center

    Houston, United States

    25 h-index

    109 publications

    7.9K citations

  5. Istituti di Ricovero e Cura a Carattere Scientifico

    Rome, Italy

    25 h-index

    158 publications

    9.2K citations

  6. Inserm

    Paris, France

    24 h-index

    120 publications

    7.7K citations

  7. Princess Margaret Cancer Centre

    Toronto, Canada

    24 h-index

    169 publications

    20.9K citations

  8. Assistance Publique – Hôpitaux de Paris

    Paris, France

    23 h-index

    119 publications

    10.3K citations

1–8 of 2.9K

Venues

  1. Journal of Clinical Oncology

    240 publications · 23.7K citations

    73

    h-index

  2. Annals of Oncology

    67 publications · 3.7K citations

    37

    h-index

  3. PubMed

    Repository · 146 publications · 4.4K citations

    34

    h-index

  4. Cancer

    40 publications · 2.2K citations

    30

    h-index

  5. Lung Cancer

    46 publications · 1.6K citations

    26

    h-index

1–5