Annual Review of Biochemistry · 1961 · 130 citations · 0 references
Life SciencesBiochemistryDevelopmental BiologyCell DifferentiationCell SignalingOrganogenesisAnimal Cell CultureCell GrowthDevelopmental Cell SignalingDevelopmental Signaling PathwaysMammalian Cell CultureMammalian DevelopmentCell Growth RegulationDevelopmental Growth RegulationHippo SignalingHippo Signaling PathwayOrgan Size ControlTissue GrowthTissue Growth ControlTissue Growth Regulation
The Hippo pathway was initially discovered in Drosophila melanogaster as a key regulator of tissue growth. It is an evolutionarily conserved signaling cascade regulating numerous biological processes, including cell growth and fate decision, organ size ...Read More